New JAMA Internal Medicine study found certain classes on anticholinergic drugs increase odds of dementia by 50 percent.
Tuesday, June 25th 2019, 10:13 AM EDT by Katelyn Massarelli
CNN – New JAMA Internal Medicine study found certain classes on anticholinergic drugs increase odds of dementia by 50 percent.
The certain classes of anticholinergic drugs include antidepressants, bladder antimuscarinics, antipsychotics and antiepileptic drugs.
Those associated with a total anticholinergic exposure of more than 1,095 daily doses within a 10-day period increase their chances.
“This is important information for physicians to know when considering whether to prescribe these drugs,”Carol Coupland, professor of medical statistics in primary care at the University of Nottingham said. “This is an observational study so no firm conclusions can be drawn about whether these anticholinergic drugs cause dementia.”
She said that people taking these medications should not to stop them without consulting with their doctor first, as that could be harmful.
The researchers found no significant increases in dementia risk associated with antihistamines, skeletal muscle relaxants, gastrointestinal antispasmodics, antiarrhythmics, or antimuscarinic bronchodilators, according to the data.